The error of mankind's use of science

     We must now consider whether there is any direct way of impairing good heredity. It is currently believed that there are certain substances, popularly known as "racial-poisons," which are capable of affecting the germ-plasm adversely and permanently in spite of its isolation and protection. For example, the literature of alcoholism, and much of the literature of eugenics, abounds with statements to the effect that alcohol originates degeneracy in the human race. The proof or disproof of this proposition must depend in the last analysis on direct observation and carefully controlled experiments.
     As the latter cannot be made feasibly on man, a number of students have taken up the problem by using small animals which are easily handled in laboratories. Many of these experiments are so imperfect in method that, when carefully examined, they are found to possess little or no value as evidence on the point here discussed. Hodge, Mairet and Combemale, for example, have published data which convinced them that the germ-plasm of dogs was injured by the administration of alcohol. The test was the quality of offspring directly produced by the intoxicated animals under experiment. But the number of dogs used was too small to be conclusive, and there was no "control": hence these experiments carry little weight.
     Ozine, Fere and Stockard have shown that the effect of alcohol on hen's eggs is to produce malformed embryos. This, however, is a case of influencing the development of the individual, rather than the germ-plasm. Evidence is abundant that individual development can be harmed by alcohol, but the experiments with eggs are not to the point of our present purpose. The conclusions have in general been in favor of injury to the germ-plasm, but the experiments were inadequate in extent. Laitinen experimented on rabbits and guinea pigs, but he used small doses and secured only negative results. Several series of experiments with rats indicate that if the dosage is large enough, the offspring can be affected. The science of eugenics consists of a foundation of biology and a superstructure of sociology.
     Galton, its founder, emphasized both parts in due proportion. Until recently, however, most sociologists have been either indifferent or hostile to eugenics, and the science has been left for the most part in the hands of biologists, who have naturally worked most on the foundations and neglected the superstructure. Although we are not disposed to minimize the importance of the biological part, we think it desirable that the means of applying the biological principles should be more carefully studied. Emphasis has rather been laid on the practical means by which society may encourage the reproduction of superior persons and discourage that of inferiors. We assume that in general, a eugenically superior or desirable person has, to a greater degree than the average, the germinal basis for the following characteristics: to live past maturity, to reproduce adequately, to live happily and to make contributions to the productivity, happiness, and progress of society. It is desirable to discriminate as much as possible between the possession of the germinal basis and the observed achievement, since the latter consists of the former plus or minus environmental influence. But where the amount of modification is too obscure to be detected, it is advantageous to take the demonstrated achievement as a tentative measure of the germinal basis. The problem of eugenics is to make such legal, social and economic adjustments that (1) a larger proportion of superior persons will have children than at present, (2) that the average number of offspring of each superior person will be greater than at present, (3) that the most inferior persons will have no children, and finally that (4) other inferior persons will have fewer children than now. The science of eugenics is still young and much of its program must be tentative and subject to the test of actual experiment. It is more important that the student acquire the habit of looking at society from a biological as well as a sociological point of view, than that he put his faith in the efficacy of any particular mode of procedure. Nice, using very small numbers of white mice, subjected them not only to alcohol, but to caffeine, nicotine, and tobacco smoke. The fecundity of all these sets of mice was higher than that of the untreated ones used as control; all of them gained in weight; of 707 young, none was deformed, none stillborn, and there was only one abortion. The young of the alcoholized mice surpassed all others in growth. The dosage Nice employed was too small, however, to give his experiment great weight. At the University of Wisconsin, Leon J. Cole has been treating male rabbits with alcohol and reports that "what appear to be decisive results have already been obtained. In the case of alcoholic poisoning of the male the most marked result has been a lessening of his efficiency as a sire, the alcohol apparently having had some effect on the vitality of his spermatozoa." His experiment is properly planned and carried out, but so far as results have been made public, they do not appear to afford conclusive evidence that alcohol originates degeneracy in offspring. The long-continued and carefully conducted experiment of Charles R. Stockard at the Cornell Medical College is most widely quoted in this connection. He works with guinea-pigs. The animals are intoxicated daily, six days in the week, by inhaling the fumes of alcohol to the point where they show evident signs of its influence; their condition may thus be compared to that of the toper who never gets "dead drunk" but is never entirely sober. Treatment of this sort for a period as long as three years produces no apparent bad effect on the individuals; they continue to grow and become fat and vigorous, taking plenty of food and behaving in a normal manner in every particular. Some of them have been killed from time to time, and all the tissues, including the reproductive glands, have been found perfectly normal. "The treated animals are, therefore, little changed or injured so far as their behavior and structure goes. Nevertheless, the effects of the treatment are most decidedly indicated by the type of offspring to which they give rise, whether they are mated together or with normal individuals." The error of mankind's use of science